Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients.

Rhind, Shawn G; Crnko, Naomi T; Baker, Andrew J; Morrison, Laurie J; Shek, Pang N; Scarpelini, Sandro; Rizoli, Sandro B

Rhind, Shawn G; Crnko, Naomi T; Baker, Andrew J; Morrison, Laurie J; Shek, Pang N; Scarpelini, Sandro; Rizoli, Sandro B.

Affiliation

Rhind SG; Defence Research and Development Canada, Toronto, Canada. shawn.rhind@drdc-rddc.gc.ca

J Neuroinflammation ; 7: 5, 2010 Jan 18.

Article in En | MEDLINE | ID: mdl-20082712

Subject(s)

Blood Coagulation/drug effects; Brain Injuries; Inflammation/drug therapy; Resuscitation/methods; Saline Solution, Hypertonic/pharmacology; Saline Solution, Hypertonic/therapeutic use; Adult; Analysis of Variance; Antigens, CD/blood; Blood Coagulation/physiology; Brain Injuries/blood; Brain Injuries/complications; Brain Injuries/drug therapy; Brain Injuries/pathology; Cytokines/blood; Dextrans/pharmacology; Dextrans/therapeutic use; Enzyme-Linked Immunosorbent Assay/methods; Female; Fibrin Fibrinogen Degradation Products/metabolism; Glasgow Coma Scale; Humans; Inflammation/etiology; Leukocytes/drug effects; Male; Middle Aged; Statistics, Nonparametric; Thrombomodulin/blood; Thromboplastin/metabolism; Time Factors; Vascular Cell Adhesion Molecule-1/metabolism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Resuscitation / Saline Solution, Hypertonic / Blood Coagulation / Brain Injuries / Inflammation Type of study: Clinical_trials / Etiology_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Year: 2010 Type: Article

Fulltext

XML

PubMed Links

Search on Google