Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2.

Celum, C; Wald, A; Lingappa, J R; Magaret, A S; Wang, R S; Mugo, N; Mujugira, A; Baeten, J M; Mullins, J I; Hughes, J P; Bukusi, E A; Cohen, C R; Katabira, E; Ronald, A; Kiarie, J; Farquhar, C; Stewart, G J; Makhema, J; Essex, M; Were, E; Fife, K H; de Bruyn, G; Gray, G E; McIntyre, J A; Manongi, R; Kapiga, S; Coetzee, D; Allen, S; Inambao, M; Kayitenkore, K; Karita, E; Kanweka, W; Delany, S; Rees, H; Vwalika, B; Stevens, W; Campbell, M S; Thomas, K K; Coombs, R W; Morrow, R; Whittington, W L H; McElrath, M J; Barnes, L; Ridzon, R; Corey, L

Celum, C; Wald, A; Lingappa, J R; Magaret, A S; Wang, R S; Mugo, N; Mujugira, A; Baeten, J M; Mullins, J I; Hughes, J P; Bukusi, E A; Cohen, C R; Katabira, E; Ronald, A; Kiarie, J; Farquhar, C; Stewart, G J; Makhema, J; Essex, M; Were, E; Fife, K H; de Bruyn, G; Gray, G E; McIntyre, J A; Manongi, R; Kapiga, S; Coetzee, D; Allen, S; Inambao, M; Kayitenkore, K; Karita, E; Kanweka, W; Delany, S; Rees, H; Vwalika, B; Stevens, W; Campbell, M S; Thomas, K K; Coombs, R W; Morrow, R; Whittington, W L H; McElrath, M J; Barnes, L; Ridzon, R; Corey, L.

Affiliation

Celum C; Department of Global Health, University of Washington, Harborview Medical Center, 325 Ninth Ave., Box 359927, Seattle, WA 98104, USA.

N Engl J Med ; 362(5): 427-39, 2010 Feb 04.

Article in En | MEDLINE | ID: mdl-20089951

Subject(s)

AIDS-Related Opportunistic Infections/drug therapy; Acyclovir/therapeutic use; Antiviral Agents/therapeutic use; HIV Infections/transmission; HIV-1; Herpes Genitalis/drug therapy; Herpesvirus 2, Human; Acyclovir/adverse effects; Adolescent; Adult; Antiviral Agents/adverse effects; CD4 Lymphocyte Count; Female; Follow-Up Studies; HIV Infections/complications; HIV-1/genetics; HIV-1/isolation & purification; Herpes Genitalis/complications; Humans; Intention to Treat Analysis; Kaplan-Meier Estimate; Male; Patient Compliance; Pregnancy; RNA, Viral/blood; Unsafe Sex/statistics & numerical data; Young Adult

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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Acyclovir / Herpes Genitalis / HIV Infections / HIV-1 / AIDS-Related Opportunistic Infections / Herpesvirus 2, Human Type of study: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Female / Humans / Male / Pregnancy Language: En Year: 2010 Type: Article

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