zeta-Crystallin is a bcl-2 mRNA binding protein involved in bcl-2 overexpression in T-cell acute lymphocytic leukemia.

Lapucci, Andrea; Lulli, Matteo; Amedei, Amedeo; Papucci, Laura; Witort, Ewa; Di Gesualdo, Federico; Bertolini, Francesco; Brewer, Gary; Nicolin, Angelo; Bevilacqua, Annamaria; Schiavone, Nicola; Morello, Dominique; Donnini, Martino; Capaccioli, Sergio

Lapucci, Andrea; Lulli, Matteo; Amedei, Amedeo; Papucci, Laura; Witort, Ewa; Di Gesualdo, Federico; Bertolini, Francesco; Brewer, Gary; Nicolin, Angelo; Bevilacqua, Annamaria; Schiavone, Nicola; Morello, Dominique; Donnini, Martino; Capaccioli, Sergio.

Affiliation

Lapucci A; Department of Experimental Pathology and Oncology, University of Florence, Florence, Italy.

FASEB J ; 24(6): 1852-65, 2010 Jun.

Article in En | MEDLINE | ID: mdl-20103721

Subject(s)

3' Untranslated Regions/physiology; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/metabolism; Proto-Oncogene Proteins c-bcl-2/metabolism; RNA, Messenger/metabolism; zeta-Crystallins/metabolism; Blotting, Western; Cytoplasm/drug effects; Cytoplasm/metabolism; Female; Gene Expression Regulation; Humans; Immunoprecipitation; Male; Middle Aged; Phytohemagglutinins; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/genetics; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology; Proto-Oncogene Proteins c-bcl-2/genetics; RNA, Messenger/genetics; RNA, Small Interfering/pharmacology; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; T-Lymphocytes/drug effects; T-Lymphocytes/pathology; zeta-Crystallins/antagonists & inhibitors; zeta-Crystallins/genetics

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Full text: 1 Database: MEDLINE Main subject: RNA, Messenger / Proto-Oncogene Proteins c-bcl-2 / 3' Untranslated Regions / Zeta-Crystallins / Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Limits: Female / Humans / Male / Middle aged Language: En Year: 2010 Type: Article

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