Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome.

Miao, Edward A; Mao, Dat P; Yudkovsky, Natalya; Bonneau, Richard; Lorang, Cynthia G; Warren, Sarah E; Leaf, Irina A; Aderem, Alan

Miao, Edward A; Mao, Dat P; Yudkovsky, Natalya; Bonneau, Richard; Lorang, Cynthia G; Warren, Sarah E; Leaf, Irina A; Aderem, Alan.

Affiliation

Miao EA; Institute for Systems Biology, Seattle, WA 98103, USA.

Proc Natl Acad Sci U S A ; 107(7): 3076-80, 2010 Feb 16.

Article in En | MEDLINE | ID: mdl-20133635

Subject(s)

Apoptosis Regulatory Proteins/immunology; Bacterial Infections/immunology; Bacterial Proteins/immunology; Calcium-Binding Proteins/immunology; Caspase 1/immunology; Immunity, Innate/immunology; Membrane Proteins/metabolism; Animals; Apoptosis Regulatory Proteins/genetics; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Calcium-Binding Proteins/genetics; Caspase 1/metabolism; Membrane Proteins/immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Conformation; Transfection

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Full text: 1 Database: MEDLINE Main subject: Bacterial Infections / Bacterial Proteins / Calcium-Binding Proteins / Caspase 1 / Apoptosis Regulatory Proteins / Immunity, Innate / Membrane Proteins Type of study: Diagnostic_studies Limits: Animals Language: En Year: 2010 Type: Article

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