Parity-induced decrease in systemic growth hormone alters mammary gland signaling: a potential role in pregnancy protection from breast cancer.

Dearth, Robert K; Delgado, David A; Hiney, Jill K; Pathiraja, Thushangi; Oesterreich, Steffi; Medina, Dan; Dees, W Les; Lee, Adrian V

Dearth, Robert K; Delgado, David A; Hiney, Jill K; Pathiraja, Thushangi; Oesterreich, Steffi; Medina, Dan; Dees, W Les; Lee, Adrian V.

Affiliation

Dearth RK; Breast Center, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

Cancer Prev Res (Phila) ; 3(3): 312-21, 2010 Mar.

Article in En | MEDLINE | ID: mdl-20145191

Subject(s)

Growth Hormone/metabolism; Insulin-Like Growth Factor I/metabolism; Mammary Glands, Animal/metabolism; Mammary Neoplasms, Experimental/prevention & control; Parity; Animals; Enzyme-Linked Immunosorbent Assay; Female; Growth Hormone/genetics; Immunoblotting; Immunoenzyme Techniques; Insulin-Like Growth Factor I/genetics; Mammary Neoplasms, Experimental/chemically induced; Pregnancy; Pregnancy, Animal; RNA, Messenger/genetics; RNA, Messenger/metabolism; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

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Full text: 1 Database: MEDLINE Main subject: Parity / Insulin-Like Growth Factor I / Growth Hormone / Mammary Glands, Animal / Mammary Neoplasms, Experimental Type of study: Prognostic_studies Limits: Animals / Pregnancy Language: En Year: 2010 Type: Article

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