Activin A induces neuronal differentiation and survival via ALK4 in a SMAD-independent manner in a subpopulation of human neuroblastomas.

Suzuki, Kotaro; Kobayashi, Tomomi; Funatsu, Osamu; Morita, Akinori; Ikekita, Masahiko

Suzuki, Kotaro; Kobayashi, Tomomi; Funatsu, Osamu; Morita, Akinori; Ikekita, Masahiko.

Affiliation

Suzuki K; Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan.

Biochem Biophys Res Commun ; 394(3): 639-45, 2010 Apr 09.

Article in En | MEDLINE | ID: mdl-20226172

Subject(s)

Activin Receptors, Type I/metabolism; Activins/metabolism; Neurogenesis; Neurons/cytology; Smad Proteins/metabolism; Activins/pharmacology; Adult; Cell Line, Tumor; Cell Nucleus/metabolism; Cell Survival; Humans; Male; Neurons/metabolism; Phosphorylation; Promoter Regions, Genetic; Smad2 Protein/metabolism; Smad3 Protein/metabolism; Smad4 Protein/metabolism; Transcriptional Activation; Transforming Growth Factor beta/metabolism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Activins / Activin Receptors, Type I / Smad Proteins / Neurogenesis / Neurons Limits: Adult / Humans / Male Language: En Year: 2010 Type: Article

Fulltext

XML

PubMed Links

Search on Google