Mycophenolic acid differentially affects dendritic cell maturation induced by tumor necrosis factor-alpha and lipopolysaccharide through a different modulation of MAPK signaling.

Faugaret, Delphine; Lemoine, Roxane; Baron, Christophe; Lebranchu, Yvon; Velge-Roussel, Florence

Faugaret, Delphine; Lemoine, Roxane; Baron, Christophe; Lebranchu, Yvon; Velge-Roussel, Florence.

Affiliation

Faugaret D; EA 4245 Cellules Dendritiques, Immunomodulation et Greffes, Université François Rabelais, IFR-136 Agents Transmissibles et Infectiologie, UFR de Médecine, 10 Bd Tonnellé, 37000 Tours, France.

Mol Immunol ; 47(9): 1848-59, 2010 May.

Article in En | MEDLINE | ID: mdl-20334925

Subject(s)

Dendritic Cells/drug effects; Lipopolysaccharides/pharmacology; MAP Kinase Signaling System/drug effects; Mycophenolic Acid/pharmacology; Tumor Necrosis Factor-alpha/pharmacology; Antibiotics, Antineoplastic/pharmacology; Blotting, Western; Cell Differentiation/drug effects; Cell Differentiation/immunology; Cells, Cultured; Cytokines/metabolism; Dendritic Cells/immunology; Dendritic Cells/metabolism; Flow Cytometry; Humans; Immunophenotyping; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinase 3/metabolism; Phosphorylation/drug effects; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Database: MEDLINE Main subject: Dendritic Cells / Lipopolysaccharides / Tumor Necrosis Factor-alpha / MAP Kinase Signaling System / Mycophenolic Acid Limits: Humans Language: En Year: 2010 Type: Article

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