Acute pharmacological modulation of mGluR8 reduces measures of anxiety.

Duvoisin, Robert M; Pfankuch, Tim; Wilson, Julie M; Grabell, Julie; Chhajlani, Vijay; Brown, Dean G; Johnson, Edwin; Raber, Jacob

Duvoisin, Robert M; Pfankuch, Tim; Wilson, Julie M; Grabell, Julie; Chhajlani, Vijay; Brown, Dean G; Johnson, Edwin; Raber, Jacob.

Affiliation

Duvoisin RM; Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, OR, USA.

Behav Brain Res ; 212(2): 168-73, 2010 Oct 15.

Article in En | MEDLINE | ID: mdl-20385173

Subject(s)

Anxiety/metabolism; Receptors, Metabotropic Glutamate/metabolism; Acetanilides/pharmacology; Animals; Anxiety/drug therapy; Apolipoproteins E/genetics; Apolipoproteins E/metabolism; Auditory Perception/drug effects; Auditory Perception/physiology; Benzoates/pharmacology; Central Nervous System Agents/pharmacology; Glycine/analogs & derivatives; Glycine/pharmacology; Male; Maze Learning/drug effects; Maze Learning/physiology; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuropsychological Tests; Receptors, Metabotropic Glutamate/agonists; Reflex, Startle/drug effects; Reflex, Startle/physiology; Thioglycolates/pharmacology; Time Factors

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Full text: 1 Database: MEDLINE Main subject: Anxiety / Receptors, Metabotropic Glutamate Limits: Animals Language: En Year: 2010 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Anxiety / Receptors, Metabotropic Glutamate Limits: Animals Language: En Year: 2010 Type: Article