Rotavirus nonstructural protein 1 suppresses virus-induced cellular apoptosis to facilitate viral growth by activating the cell survival pathways during early stages of infection.

Bagchi, Parikshit; Dutta, Dipanjan; Chattopadhyay, Shiladitya; Mukherjee, Anupam; Halder, Umesh Chandra; Sarkar, Sagartirtha; Kobayashi, Nobumichi; Komoto, Satoshi; Taniguchi, Koki; Chawla-Sarkar, Mamta

Bagchi, Parikshit; Dutta, Dipanjan; Chattopadhyay, Shiladitya; Mukherjee, Anupam; Halder, Umesh Chandra; Sarkar, Sagartirtha; Kobayashi, Nobumichi; Komoto, Satoshi; Taniguchi, Koki; Chawla-Sarkar, Mamta.

Affiliation

Bagchi P; Division of Virology, National Institute of Cholera and Enteric Diseases, P-33, C.I.T. Road, Scheme-XM, Beliaghata, Kolkata 700010, West Bengal, India.

J Virol ; 84(13): 6834-45, 2010 Jul.

Article in En | MEDLINE | ID: mdl-20392855

Subject(s)

Apoptosis; Rotavirus/pathogenicity; Viral Nonstructural Proteins/physiology; Virulence Factors/physiology; Animals; Cell Line; Cell Survival; Haplorhini; Humans; Immunoprecipitation; Mutation; Phosphatidylinositol 3-Kinases/metabolism; Protein Binding; Rotavirus/growth & development; Viral Nonstructural Proteins/genetics; Virulence Factors/genetics

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Full text: 1 Database: MEDLINE Main subject: Viral Nonstructural Proteins / Apoptosis / Rotavirus / Virulence Factors Limits: Animals / Humans Language: En Year: 2010 Type: Article

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