Altered natural killer (NK) cell frequency and phenotype in latent autoimmune diabetes in adults (LADA) prior to insulin deficiency.

Akesson, C; Uvebrant, K; Oderup, C; Lynch, K; Harris, R A; Lernmark, A; Agardh, C-D; Cilio, C M

Akesson, C; Uvebrant, K; Oderup, C; Lynch, K; Harris, R A; Lernmark, A; Agardh, C-D; Cilio, C M.

Affiliation

Akesson C; Cellular Autoimmunity Unit, Department of Clinical Sciences, Malmö University Hospital, Malmö, Sweden.

Clin Exp Immunol ; 161(1): 48-56, 2010 Jul 01.

Article in En | MEDLINE | ID: mdl-20408863

Subject(s)

Diabetes Mellitus, Type 1/immunology; Killer Cells, Natural/immunology; Lymphopenia/etiology; Prediabetic State/immunology; Adult; Age of Onset; Aged; Autoantibodies/blood; Autoantibodies/immunology; Autoantigens/immunology; Diabetes Mellitus, Type 1/blood; Diabetes Mellitus, Type 1/diagnosis; Diabetes Mellitus, Type 2/diagnosis; Diagnosis, Differential; Disease Progression; Female; Glutamate Decarboxylase/immunology; HLA-DQ Antigens/analysis; HLA-DQ beta-Chains; Humans; Immune Tolerance; Immunophenotyping; Insulin/blood; Insulin/immunology; Lymphocyte Count; Lymphopenia/immunology; Male; Middle Aged; NK Cell Lectin-Like Receptor Subfamily K/blood; Prediabetic State/blood; Receptors, KIR3DL1/blood; Receptors, KIR3DL1/deficiency; Risk; T-Lymphocyte Subsets/immunology

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Full text: 1 Database: MEDLINE Main subject: Prediabetic State / Killer Cells, Natural / Diabetes Mellitus, Type 1 / Lymphopenia Type of study: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Year: 2010 Type: Article

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