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DBM1285 suppresses tumor necrosis factor alpha production by blocking p38 mitogen-activated protein kinase/mitogen-activated protein kinase-activated protein kinase 2 signaling pathway.
Kang, Jong Soon; Kim, Hwan Mook; Choi, In Young; Han, Sang-Bae; Yoon, Yeo Dae; Lee, Hyunju; Park, Ki Hwan; Cho, Ig Jun; Lee, Chang Woo; Lee, Kiho; Lee, Ki Hoon; Park, Song-Kyu.
Affiliation
  • Kang JS; Bioevaluation Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Cheongwon, Chungbuk, Republic of Korea.
J Pharmacol Exp Ther ; 334(2): 657-64, 2010 Aug.
Article in En | MEDLINE | ID: mdl-20427474
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Full text: 1 Database: MEDLINE Main subject: Pyrimidines / Thiazoles / Anti-Inflammatory Agents, Non-Steroidal / Tumor Necrosis Factor-alpha / Protein Serine-Threonine Kinases / P38 Mitogen-Activated Protein Kinases / Intracellular Signaling Peptides and Proteins Type of study: Prognostic_studies Limits: Animals Language: En Year: 2010 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Pyrimidines / Thiazoles / Anti-Inflammatory Agents, Non-Steroidal / Tumor Necrosis Factor-alpha / Protein Serine-Threonine Kinases / P38 Mitogen-Activated Protein Kinases / Intracellular Signaling Peptides and Proteins Type of study: Prognostic_studies Limits: Animals Language: En Year: 2010 Type: Article