Therapeutic effects of a recombinant mutant of the human ciliary neurotrophic factor in a mouse model of metabolic syndrome.

Cui, Ming-Xia; Jiang, Jun-Feng; Zheng, Rong-Liang; Li, Rui-Lian; Wang, Lei; Li, Wen-Guang; Gao, Ming-Tang; Yang, Li-Ning; Dou, Jin-Yan; Wu, Yong-Jie

Cui, Ming-Xia; Jiang, Jun-Feng; Zheng, Rong-Liang; Li, Rui-Lian; Wang, Lei; Li, Wen-Guang; Gao, Ming-Tang; Yang, Li-Ning; Dou, Jin-Yan; Wu, Yong-Jie.

Affiliation

Cui MX; Institute of Pharmacology, School of Basic Medical Science, Lanzhou University, Gansu Province Key Laboratory of Preclinical Study for New Drugs, Lanzhou, China.

Pharmazie ; 65(4): 279-83, 2010 Apr.

Article in En | MEDLINE | ID: mdl-20432625

Subject(s)

Ciliary Neurotrophic Factor/therapeutic use; Metabolic Syndrome/drug therapy; Animals; Antioxidants/metabolism; Blood Glucose/metabolism; Ciliary Neurotrophic Factor/blood; Diet; Dietary Fats; Fatty Liver/drug therapy; Fatty Liver/etiology; Humans; Insulin Resistance; Lipids/blood; Liver Function Tests; Male; Malondialdehyde/metabolism; Mice; Mice, Inbred C57BL; Obesity/drug therapy; Obesity/etiology; Recombinant Proteins/therapeutic use

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Database: MEDLINE Main subject: Ciliary Neurotrophic Factor / Metabolic Syndrome Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans / Male Language: En Year: 2010 Type: Article

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