The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway.

Shah, Zahoor A; Li, Rung-chi; Ahmad, Abdullah S; Kensler, Thomas W; Yamamoto, Masayuki; Biswal, Shyam; Doré, Sylvain

Shah, Zahoor A; Li, Rung-chi; Ahmad, Abdullah S; Kensler, Thomas W; Yamamoto, Masayuki; Biswal, Shyam; Doré, Sylvain.

Affiliation

Shah ZA; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

J Cereb Blood Flow Metab ; 30(12): 1951-61, 2010 Dec.

Article in En | MEDLINE | ID: mdl-20442725

Subject(s)

Catechin/therapeutic use; Heme Oxygenase-1/metabolism; Infarction, Middle Cerebral Artery/prevention & control; Membrane Proteins/metabolism; NF-E2-Related Factor 2/metabolism; Signal Transduction; Animals; Cells, Cultured; Cytoprotection/drug effects; Heme Oxygenase-1/deficiency; Infarction, Middle Cerebral Artery/chemically induced; Membrane Proteins/deficiency; Mice; Mice, Knockout; N-Methylaspartate; NF-E2-Related Factor 2/deficiency; Oxidative Stress; Protein Transport

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Full text: 1 Database: MEDLINE Main subject: Signal Transduction / Catechin / Infarction, Middle Cerebral Artery / Heme Oxygenase-1 / NF-E2-Related Factor 2 / Membrane Proteins Limits: Animals Language: En Year: 2010 Type: Article

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