K+ channel openers restore verapamil-inhibited lung fluid resolution and transepithelial ion transport.

Han, Dong-Yun; Nie, Hong-Guang; Gu, Xiu; Nayak, Ramesh C; Su, Xue-Feng; Fu, Jian; Chang, Yongchang; Rao, Vijay; Ji, Hong-Long

Han, Dong-Yun; Nie, Hong-Guang; Gu, Xiu; Nayak, Ramesh C; Su, Xue-Feng; Fu, Jian; Chang, Yongchang; Rao, Vijay; Ji, Hong-Long.

Affiliation

Han DY; Department of Biochemistry, University of Texas Health Science Center at Tyler, Tyler, TX 75708, USA.

Respir Res ; 11: 65, 2010 May 27.

Article in En | MEDLINE | ID: mdl-20507598

Subject(s)

Benzimidazoles/pharmacology; Calcium Channel Blockers/toxicity; Epithelial Cells/drug effects; Epithelial Sodium Channels/drug effects; Lung/drug effects; Minoxidil/pharmacology; Potassium Channels/agonists; Pulmonary Edema/drug therapy; Pyridines/pharmacology; Thiones/pharmacology; Verapamil/toxicity; Animals; Calcium/metabolism; Calcium Signaling/drug effects; Dose-Response Relationship, Drug; Epithelial Cells/metabolism; Epithelial Sodium Channels/genetics; Epithelial Sodium Channels/metabolism; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels/agonists; Intermediate-Conductance Calcium-Activated Potassium Channels/metabolism; KATP Channels/agonists; KATP Channels/metabolism; Lung/metabolism; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Potassium/metabolism; Potassium Channels/metabolism; Pulmonary Edema/chemically induced; Pulmonary Edema/metabolism; Sodium/metabolism; Xenopus laevis

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Full text: 1 Database: MEDLINE Main subject: Pulmonary Edema / Pyridines / Thiones / Benzimidazoles / Calcium Channel Blockers / Verapamil / Potassium Channels / Epithelial Cells / Epithelial Sodium Channels / Lung Limits: Animals / Humans / Male Language: En Year: 2010 Type: Article

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