Bulky high-mannose-type N-glycan blocks the taste-modifying activity of miraculin.

Ito, Keisuke; Sugawara, Taishi; Koizumi, Ayako; Nakajima, Ken-Ichiro; Shimizu-Ibuka, Akiko; Shiroishi, Mitsunori; Asada, Hidetsugu; Yurugi-Kobayashi, Takami; Shimamura, Tatsuro; Asakura, Tomiko; Masuda, Katsuyoshi; Ishiguro, Masaji; Misaka, Takumi; Iwata, So; Kobayashi, Takuya; Abe, Keiko

Ito, Keisuke; Sugawara, Taishi; Koizumi, Ayako; Nakajima, Ken-Ichiro; Shimizu-Ibuka, Akiko; Shiroishi, Mitsunori; Asada, Hidetsugu; Yurugi-Kobayashi, Takami; Shimamura, Tatsuro; Asakura, Tomiko; Masuda, Katsuyoshi; Ishiguro, Masaji; Misaka, Takumi; Iwata, So; Kobayashi, Takuya; Abe, Keiko.

Affiliation

Ito K; Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.

Biochim Biophys Acta ; 1800(9): 986-92, 2010 Sep.

Article in En | MEDLINE | ID: mdl-20542090

Subject(s)

Glycoproteins; Polysaccharides; Receptors, G-Protein-Coupled/agonists; Recombinant Proteins; Taste/drug effects; Glycoproteins/biosynthesis; Glycoproteins/genetics; Glycoproteins/pharmacology; Humans; Polysaccharides/biosynthesis; Polysaccharides/genetics; Polysaccharides/pharmacology; Receptors, G-Protein-Coupled/metabolism; Recombinant Proteins/biosynthesis; Recombinant Proteins/genetics; Recombinant Proteins/pharmacology; Saccharomyces cerevisiae/genetics; Taste/physiology

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Full text: 1 Database: MEDLINE Main subject: Polysaccharides / Taste / Recombinant Proteins / Glycoproteins / Receptors, G-Protein-Coupled Limits: Humans Language: En Year: 2010 Type: Article

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