Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2.

Warren, Sarah E; Armstrong, Abraham; Hamilton, M Kristina; Mao, Dat P; Leaf, Irina A; Miao, Edward A; Aderem, Alan

Warren, Sarah E; Armstrong, Abraham; Hamilton, M Kristina; Mao, Dat P; Leaf, Irina A; Miao, Edward A; Aderem, Alan.

Affiliation

Warren SE; Institute for Systems Biology, Seattle, WA 98103, USA.

J Immunol ; 185(2): 818-21, 2010 Jul 15.

Article in En | MEDLINE | ID: mdl-20562263

Subject(s)

DNA, Bacterial/immunology; Listeria monocytogenes/immunology; Macrophages/immunology; Nuclear Proteins/immunology; Animals; Apoptosis Regulatory Proteins/genetics; Apoptosis Regulatory Proteins/immunology; Apoptosis Regulatory Proteins/metabolism; Calcium-Binding Proteins/genetics; Calcium-Binding Proteins/immunology; Calcium-Binding Proteins/metabolism; Carrier Proteins/genetics; Carrier Proteins/immunology; Carrier Proteins/metabolism; Cytosol/immunology; Cytosol/microbiology; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; Host-Pathogen Interactions; Interleukin-1beta/metabolism; L Cells; Listeria monocytogenes/genetics; Listeria monocytogenes/physiology; Macrophages/metabolism; Macrophages/microbiology; Mice; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Nuclear Proteins/genetics; Phagosomes/immunology; Phagosomes/metabolism; Phagosomes/microbiology; RNA Interference

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Full text: 1 Database: MEDLINE Main subject: DNA, Bacterial / Nuclear Proteins / Listeria monocytogenes / Macrophages Type of study: Prognostic_studies Limits: Animals Language: En Year: 2010 Type: Article

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