Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development.

Qi, Hank H; Sarkissian, Madathia; Hu, Gang-Qing; Wang, Zhibin; Bhattacharjee, Arindam; Gordon, D Benjamin; Gonzales, Michelle; Lan, Fei; Ongusaha, Pat P; Huarte, Maite; Yaghi, Nasser K; Lim, Huijun; Garcia, Benjamin A; Brizuela, Leonardo; Zhao, Keji; Roberts, Thomas M; Shi, Yang

Qi, Hank H; Sarkissian, Madathia; Hu, Gang-Qing; Wang, Zhibin; Bhattacharjee, Arindam; Gordon, D Benjamin; Gonzales, Michelle; Lan, Fei; Ongusaha, Pat P; Huarte, Maite; Yaghi, Nasser K; Lim, Huijun; Garcia, Benjamin A; Brizuela, Leonardo; Zhao, Keji; Roberts, Thomas M; Shi, Yang.

Affiliation

Qi HH; Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature ; 466(7305): 503-7, 2010 Jul 22.

Article in En | MEDLINE | ID: mdl-20622853

Subject(s)

Brain/embryology; Brain/enzymology; Head/embryology; Histone Demethylases/metabolism; Histones/metabolism; Transcription Factors/metabolism; Zebrafish Proteins/metabolism; Zebrafish/embryology; Animals; Biocatalysis; Brain/cytology; Catalytic Domain; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA, Intergenic/genetics; Gene Expression Regulation; Histone Demethylases/genetics; Histones/chemistry; Homeodomain Proteins/genetics; Humans; Jaw/cytology; Jaw/embryology; Lysine/metabolism; Mental Retardation, X-Linked/enzymology; Mental Retardation, X-Linked/genetics; Methylation; Neurons/cytology; Neurons/enzymology; Promoter Regions, Genetic; Transcription Factors/deficiency; Transcription Factors/genetics; Transcription Initiation Site; Zebrafish/metabolism; Zebrafish Proteins/genetics

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Full text: 1 Database: MEDLINE Main subject: Transcription Factors / Zebrafish / Brain / Histones / Zebrafish Proteins / Histone Demethylases / Head Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2010 Type: Article

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