Primed antigen-specific CD4+ T cells are required for NK cell activation in vivo upon Leishmania major infection.

Bihl, Franck; Pecheur, Julien; Bréart, Béatrice; Poupon, Gwenola; Cazareth, Julie; Julia, Valérie; Glaichenhaus, Nicolas; Braud, Véronique M

Bihl, Franck; Pecheur, Julien; Bréart, Béatrice; Poupon, Gwenola; Cazareth, Julie; Julia, Valérie; Glaichenhaus, Nicolas; Braud, Véronique M.

Affiliation

Bihl F; Centre National de la Recherche Scientifique/Université de Nice-Sophia Antipolis, Unité Mixte de Recherche 6097, Valbonne, France.

J Immunol ; 185(4): 2174-81, 2010 Aug 15.

Article in En | MEDLINE | ID: mdl-20624944

Subject(s)

Antigens/immunology; CD4-Positive T-Lymphocytes/immunology; Killer Cells, Natural/immunology; Leishmaniasis, Cutaneous/immunology; Amino Acid Sequence; Animals; CD4-Positive T-Lymphocytes/metabolism; Cells, Cultured; Dendritic Cells/immunology; Dendritic Cells/metabolism; Female; Flow Cytometry; Interferon-gamma/immunology; Interferon-gamma/metabolism; Interleukin-12/immunology; Interleukin-12/metabolism; Interleukin-2/genetics; Interleukin-2/immunology; Interleukin-2/metabolism; Killer Cells, Natural/metabolism; Leishmania major/immunology; Leishmaniasis, Cutaneous/parasitology; Lymphocyte Activation/immunology; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, SCID; Molecular Sequence Data; Time Factors

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Full text: 1 Database: MEDLINE Main subject: Killer Cells, Natural / CD4-Positive T-Lymphocytes / Leishmaniasis, Cutaneous / Antigens Limits: Animals Language: En Year: 2010 Type: Article

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