Inducible gene and shRNA expression in resident hematopoietic stem cells in vivo.

Laurenti, Elisa; Barde, Isabelle; Verp, Sonia; Offner, Sandra; Wilson, Anne; Quenneville, Simon; Wiznerowicz, Maciej; Macdonald, H Robson; Trono, Didier; Trumpp, Andreas

Laurenti, Elisa; Barde, Isabelle; Verp, Sonia; Offner, Sandra; Wilson, Anne; Quenneville, Simon; Wiznerowicz, Maciej; Macdonald, H Robson; Trono, Didier; Trumpp, Andreas.

Affiliation

Laurenti E; Ecole Polytechnique Fédérale de Lausanne (EPFL), ISREC - Swiss Institute for Experimental Cancer Research, School of Life Science, and Frontiers in Genetics National Center for Competence in Research, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

Stem Cells ; 28(8): 1390-8, 2010 Aug.

Article in En | MEDLINE | ID: mdl-20641037

Subject(s)

Hematopoietic Stem Cells/cytology; Hematopoietic Stem Cells/metabolism; RNA, Small Interfering/physiology; Animals; Apoptosis/drug effects; Apoptosis/genetics; Cell Cycle/drug effects; Cell Cycle/genetics; Cell Proliferation; Cells, Cultured; Doxycycline/pharmacology; Female; Flow Cytometry; Gene Expression/drug effects; Gene Expression/genetics; Genetic Vectors/genetics; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells/drug effects; Humans; Lentivirus/genetics; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Small Interfering/genetics; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53/genetics

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Hematopoietic Stem Cells / RNA, Small Interfering Limits: Animals / Female / Humans Language: En Year: 2010 Type: Article

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Hematopoietic Stem Cells / RNA, Small Interfering Limits: Animals / Female / Humans Language: En Year: 2010 Type: Article