Defining process design space for a hydrophobic interaction chromatography (HIC) purification step: application of quality by design (QbD) principles.

Jiang, Canping; Flansburg, Lisa; Ghose, Sanchayita; Jorjorian, Paul; Shukla, Abhinav A

Jiang, Canping; Flansburg, Lisa; Ghose, Sanchayita; Jorjorian, Paul; Shukla, Abhinav A.

Affiliation

Jiang C; Manufacturing Sciences & Technology, Bristol-Myers Squibb Co., East Syracuse, New York 13057, USA.

Biotechnol Bioeng ; 107(6): 985-97, 2010 Dec 15.

Article in En | MEDLINE | ID: mdl-20683852

Subject(s)

Biological Products/isolation & purification; Biotechnology/methods; Chromatography/methods; Hydrophobic and Hydrophilic Interactions

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Full text: 1 Database: MEDLINE Main subject: Biological Products / Biotechnology / Chromatography Type of study: Prognostic_studies Language: En Year: 2010 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Biological Products / Biotechnology / Chromatography Type of study: Prognostic_studies Language: En Year: 2010 Type: Article