+Antisense oligonucleotide targeting survivin inhibits growth by inducing apoptosis in human osteosarcoma cells MG-63.

Wu, Y F; Liang, X J; Liu, Y Y; Gong, W; Liu, J X; Wang, X P; Zhuang, Z Q; Guo, Y; Shen, H Y

Wu, Y F; Liang, X J; Liu, Y Y; Gong, W; Liu, J X; Wang, X P; Zhuang, Z Q; Guo, Y; Shen, H Y.

Affiliation

Wu YF; Department of Orthopaedics, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, People's Republic of China.

Neoplasma ; 57(6): 501-6, 2010.

Article in En | MEDLINE | ID: mdl-20845987

Subject(s)

Apoptosis/drug effects; Bone Neoplasms/therapy; Microtubule-Associated Proteins/antagonists & inhibitors; Oligonucleotides, Antisense/pharmacology; Osteosarcoma/therapy; Bone Neoplasms/pathology; Cell Line, Tumor; Cell Proliferation/drug effects; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins/analysis; Microtubule-Associated Proteins/genetics; Microtubule-Associated Proteins/physiology; Osteosarcoma/pathology; RNA, Messenger/analysis; Reverse Transcriptase Polymerase Chain Reaction; Survivin

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Database: MEDLINE Main subject: Bone Neoplasms / Osteosarcoma / Oligonucleotides, Antisense / Apoptosis / Microtubule-Associated Proteins Limits: Humans Language: En Year: 2010 Type: Article

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