Blockade of nerve sprouting and neuroma formation markedly attenuates the development of late stage cancer pain.

Mantyh, W G; Jimenez-Andrade, J M; Stake, J I; Bloom, A P; Kaczmarska, M J; Taylor, R N; Freeman, K T; Ghilardi, J R; Kuskowski, M A; Mantyh, P W

Mantyh, W G; Jimenez-Andrade, J M; Stake, J I; Bloom, A P; Kaczmarska, M J; Taylor, R N; Freeman, K T; Ghilardi, J R; Kuskowski, M A; Mantyh, P W.

Affiliation

Mantyh WG; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ 85724, USA. pmantyh@email.arizona.edu

Neuroscience ; 171(2): 588-98, 2010 Dec 01.

Article in En | MEDLINE | ID: mdl-20851743

Subject(s)

Bone Neoplasms/physiopathology; Nerve Fibers/pathology; Nerve Growth Factor/antagonists & inhibitors; Neuroma/prevention & control; Pain/prevention & control; Animals; Antibodies/pharmacology; Bone Neoplasms/pathology; Cell Line, Tumor; Disease Progression; Female; Mice; Neoplasm Transplantation; Nerve Fibers/drug effects; Nerve Growth Factor/immunology; Neuroma/pathology; Pain/pathology; Pain/physiopathology

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Full text: 1 Database: MEDLINE Main subject: Pain / Bone Neoplasms / Nerve Growth Factor / Nerve Fibers / Neuroma Type of study: Prognostic_studies Limits: Animals Language: En Year: 2010 Type: Article

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