Lidocaine-derivative JMF2-1 prevents ovalbumin-induced airway inflammation by regulating the function and survival of T cells.

Olsen, P C; Ferreira, T P T; Serra, M F; Farias-Filho, F A; Fonseca, B P; Viola, J P B; Cordeiro, R S B; Silva, P M R; Costa, J C S; Martins, M A

Olsen, P C; Ferreira, T P T; Serra, M F; Farias-Filho, F A; Fonseca, B P; Viola, J P B; Cordeiro, R S B; Silva, P M R; Costa, J C S; Martins, M A.

Affiliation

Olsen PC; Laboratory of Inflammation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.

Clin Exp Allergy ; 41(2): 250-9, 2011 Feb.

Article in En | MEDLINE | ID: mdl-20874831

Subject(s)

Anti-Inflammatory Agents/pharmacology; Bronchial Hyperreactivity/drug therapy; Bronchial Hyperreactivity/immunology; Lidocaine/analogs & derivatives; Ovalbumin/antagonists & inhibitors; Ovalbumin/immunology; T-Lymphocytes/drug effects; Animals; Anti-Inflammatory Agents/chemical synthesis; Anti-Inflammatory Agents/chemistry; Apoptosis/drug effects; Apoptosis/immunology; Bronchial Hyperreactivity/pathology; Cytokines/biosynthesis; Cytokines/immunology; Dexamethasone/pharmacology; Inflammation/immunology; Inflammation/prevention & control; Lidocaine/chemical synthesis; Lidocaine/chemistry; Lidocaine/pharmacology; Mice; Mice, Inbred BALB C; Mice, Transgenic; T-Lymphocytes/immunology

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Full text: 1 Database: MEDLINE Main subject: T-Lymphocytes / Ovalbumin / Bronchial Hyperreactivity / Lidocaine / Anti-Inflammatory Agents Limits: Animals Language: En Year: 2011 Type: Article

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