Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme.

Airik, Rannar; Trowe, Mark-Oliver; Foik, Anna; Farin, Henner F; Petry, Marianne; Schuster-Gossler, Karin; Schweizer, Michaela; Scherer, Gerd; Kist, Ralf; Kispert, Andreas

Airik, Rannar; Trowe, Mark-Oliver; Foik, Anna; Farin, Henner F; Petry, Marianne; Schuster-Gossler, Karin; Schweizer, Michaela; Scherer, Gerd; Kist, Ralf; Kispert, Andreas.

Affiliation

Airik R; Institut für Molekularbiologie, Medizinische Hochschule Hannover, D-30625 Hannover, Germany.

Hum Mol Genet ; 19(24): 4918-29, 2010 Dec 15.

Article in En | MEDLINE | ID: mdl-20881014

Subject(s)

Cell Differentiation; Hydronephrosis/genetics; Hydronephrosis/pathology; Mesoderm/pathology; Myocytes, Smooth Muscle/pathology; SOX9 Transcription Factor/genetics; Ureter/pathology; Animals; Cell Differentiation/genetics; Embryo, Mammalian/metabolism; Embryo, Mammalian/pathology; Extracellular Matrix/genetics; Gene Expression Regulation, Developmental; Gene Silencing; Kidney/metabolism; Kidney/pathology; Mesoderm/metabolism; Mice; Mutation/genetics; Myocytes, Smooth Muscle/metabolism; SOX9 Transcription Factor/metabolism; Ureter/growth & development; Ureter/metabolism

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Full text: 1 Database: MEDLINE Main subject: Ureter / Cell Differentiation / Myocytes, Smooth Muscle / SOX9 Transcription Factor / Hydronephrosis / Mesoderm Type of study: Risk_factors_studies Limits: Animals Language: En Year: 2010 Type: Article

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