BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model.

Shi, SongTing; Hoogaars, Willem M H; de Gorter, David J J; van Heiningen, Sandra H; Lin, Herbert Y; Hong, Charles C; Kemaladewi, Dwi U; Aartsma-Rus, Annemieke; ten Dijke, Peter; 't Hoen, Peter A C

Shi, SongTing; Hoogaars, Willem M H; de Gorter, David J J; van Heiningen, Sandra H; Lin, Herbert Y; Hong, Charles C; Kemaladewi, Dwi U; Aartsma-Rus, Annemieke; ten Dijke, Peter; 't Hoen, Peter A C.

Affiliation

Shi S; Department of Molecular Cell Biology and Centre for Biomedical Genetics, Leiden, The Netherlands.

Neurobiol Dis ; 41(2): 353-60, 2011 Feb.

Article in En | MEDLINE | ID: mdl-20940052

Subject(s)

Bone Morphogenetic Proteins/antagonists & inhibitors; Cell Differentiation/drug effects; Disease Models, Animal; Muscle, Skeletal/drug effects; Muscular Dystrophy, Duchenne/drug therapy; Muscular Dystrophy, Duchenne/genetics; Myoblasts/pathology; Phenotype; Animals; Bone Morphogenetic Proteins/metabolism; Carrier Proteins/genetics; Carrier Proteins/pharmacology; Carrier Proteins/therapeutic use; Cell Differentiation/genetics; Cell Line; Humans; Male; Mice; Mice, Inbred mdx; Mice, Knockout; Muscle, Skeletal/metabolism; Muscle, Skeletal/pathology; Muscular Dystrophy, Duchenne/pathology; Myoblasts/drug effects; Myoblasts/metabolism

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Full text: 1 Database: MEDLINE Main subject: Phenotype / Cell Differentiation / Muscle, Skeletal / Bone Morphogenetic Proteins / Muscular Dystrophy, Duchenne / Myoblasts / Disease Models, Animal Limits: Animals / Humans / Male Language: En Year: 2011 Type: Article

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