Toxicogenomic analysis of exposure to TCDD, PCB126 and PCB153: identification of genomic biomarkers of exposure to AhR ligands.

Ovando, Bladimir J; Ellison, Corie A; Vezina, Chad M; Olson, James R

Ovando, Bladimir J; Ellison, Corie A; Vezina, Chad M; Olson, James R.

Affiliation

Ovando BJ; Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York 14214, USA.

BMC Genomics ; 11: 583, 2010 Oct 19.

Article in En | MEDLINE | ID: mdl-20959002

Subject(s)

Environmental Exposure/analysis; Genome/genetics; Polychlorinated Biphenyls/toxicity; Polychlorinated Dibenzodioxins/toxicity; Receptors, Aryl Hydrocarbon/metabolism; Toxicogenetics/methods; Animals; Biomarkers/metabolism; Carcinoma, Hepatocellular/genetics; Cholangiocarcinoma/genetics; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic/drug effects; Ligands; Liver/drug effects; Liver/metabolism; Liver/pathology; Liver Neoplasms/genetics; Oligonucleotide Array Sequence Analysis; Phenotype; Rats; Rats, Sprague-Dawley

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Full text: 1 Database: MEDLINE Main subject: Genome / Polychlorinated Biphenyls / Receptors, Aryl Hydrocarbon / Toxicogenetics / Environmental Exposure / Polychlorinated Dibenzodioxins Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Year: 2010 Type: Article

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