Titin is a target of matrix metalloproteinase-2: implications in myocardial ischemia/reperfusion injury.

Ali, Mohammad A M; Cho, Woo Jung; Hudson, Bryan; Kassiri, Zamaneh; Granzier, Henk; Schulz, Richard

Ali, Mohammad A M; Cho, Woo Jung; Hudson, Bryan; Kassiri, Zamaneh; Granzier, Henk; Schulz, Richard.

Affiliation

Ali MA; Department of Pharmacology, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada.

Circulation ; 122(20): 2039-47, 2010 Nov 16.

Article in En | MEDLINE | ID: mdl-21041693

Subject(s)

Matrix Metalloproteinase 2/metabolism; Muscle Proteins/metabolism; Myocardial Reperfusion Injury/metabolism; Protein Kinases/metabolism; Animals; Connectin; Humans; Male; Matrix Metalloproteinase 2/genetics; Matrix Metalloproteinase Inhibitors; Mice; Mice, Knockout; Muscle Proteins/genetics; Myocardial Contraction/drug effects; Myocardial Contraction/genetics; Myocardial Reperfusion Injury/genetics; Myocardial Reperfusion Injury/pathology; Myocardium/metabolism; Myocardium/pathology; Myocytes, Cardiac/metabolism; Myocytes, Cardiac/pathology; Phenyl Ethers/pharmacology; Protein Kinases/genetics; Rats; Rats, Sprague-Dawley; Sarcolemma/genetics; Sarcolemma/metabolism; Sarcolemma/pathology

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Full text: 1 Database: MEDLINE Main subject: Protein Kinases / Myocardial Reperfusion Injury / Matrix Metalloproteinase 2 / Muscle Proteins Limits: Animals / Humans / Male Language: En Year: 2010 Type: Article

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