Emerging resistant Gram-negative aerobic bacilli in hospital-acquired infections.
Chemotherapy
; 56(6): 492-500, 2010.
Article
in En
| MEDLINE
| ID: mdl-21099222
ABSTRACT
The increasing emergence of serious multidrug-resistant (MDR) Gram-negative infections has led to a new health-care crisis. These infections predominately include MDR Pseudomonas aeruginosa, extended-spectrum beta-lactamase-producing Enterobacteriaceae and MDR Acinetobacter baumannii. These organisms are present in a variety of clinical settings, but there is a distinct paucity of antibiotics to effectively treat these infections. The increasing use of broad-spectrum antibiotics and lack of good stewardship have contributed to the increase in these MDR organisms. This review focuses on the main MDR Gram-negative infections contributing to the current crisis in health care, their mechanisms of resistance and various treatment options for empiric therapy.
Full text:
1
Database:
MEDLINE
Main subject:
Cross Infection
/
Gram-Negative Bacterial Infections
/
Drug Resistance, Multiple, Bacterial
/
Gram-Negative Aerobic Bacteria
/
Anti-Bacterial Agents
Limits:
Humans
Language:
En
Year:
2010
Type:
Article