Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate.

Larson, Eric T; Kim, Jessica E; Zucker, Frank H; Kelley, Angela; Mueller, Natascha; Napuli, Alberto J; Verlinde, Christophe L M J; Fan, Erkang; Buckner, Frederick S; Van Voorhis, Wesley C; Merritt, Ethan A; Hol, Wim G J

Larson, Eric T; Kim, Jessica E; Zucker, Frank H; Kelley, Angela; Mueller, Natascha; Napuli, Alberto J; Verlinde, Christophe L M J; Fan, Erkang; Buckner, Frederick S; Van Voorhis, Wesley C; Merritt, Ethan A; Hol, Wim G J.

Affiliation

Larson ET; Department of Biochemistry, University of Washington, Seattle, WA 98195-7742, USA.

Biochimie ; 93(3): 570-82, 2011 Mar.

Article in En | MEDLINE | ID: mdl-21144880

Subject(s)

Adenosine Monophosphate/analogs & derivatives; Diphosphates/metabolism; Leishmania major/enzymology; Methionine-tRNA Ligase/chemistry; Methionine-tRNA Ligase/metabolism; Methionine/analogs & derivatives; Adenine Nucleotides/metabolism; Adenosine Monophosphate/chemistry; Adenosine Monophosphate/metabolism; Amino Acid Motifs; Amino Acid Sequence; Catalytic Domain; Crystallography, X-Ray; Diphosphates/chemistry; Escherichia coli/enzymology; Gram-Negative Bacteria/enzymology; Humans; Magnesium/metabolism; Methionine/chemistry; Methionine/metabolism; Models, Molecular; Molecular Sequence Data; Protein Binding; Sequence Homology, Amino Acid; Tryptophan-tRNA Ligase/metabolism

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Full text: 1 Database: MEDLINE Main subject: Adenosine Monophosphate / Leishmania major / Diphosphates / Methionine / Methionine-tRNA Ligase Limits: Humans Language: En Year: 2011 Type: Article

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