Heparin cofactor II-thrombin complex and dermatan sulphate:chondroitin sulphate ratio are biomarkers of short- and long-term treatment effects in mucopolysaccharide diseases.

Langford-Smith, Kia Jane; Mercer, Jean; Petty, June; Tylee, Karen; Church, Heather; Roberts, Jane; Moss, Gill; Jones, Simon; Wynn, Rob; Wraith, J Ed; Bigger, Brian W

Langford-Smith, Kia Jane; Mercer, Jean; Petty, June; Tylee, Karen; Church, Heather; Roberts, Jane; Moss, Gill; Jones, Simon; Wynn, Rob; Wraith, J Ed; Bigger, Brian W.

Affiliation

Langford-Smith KJ; MPS Stem Cell Research Group, Faculty of Medical and Human Sciences, University of Manchester, Manchester, M13 9PT, UK.

J Inherit Metab Dis ; 34(2): 499-508, 2011 Apr.

Article in En | MEDLINE | ID: mdl-21170681

Subject(s)

Chondroitin Sulfates/chemistry; Dermatan Sulfate/chemistry; Glycosaminoglycans/metabolism; Heparin Cofactor II/chemistry; Thrombin/chemistry; Animals; Biomarkers/metabolism; Child; Child, Preschool; Enzyme-Linked Immunosorbent Assay/methods; Glycosaminoglycans/urine; Humans; Infant; Infant, Newborn; Mice; Neonatal Screening/methods; Treatment Outcome

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Full text: 1 Database: MEDLINE Main subject: Thrombin / Heparin Cofactor II / Chondroitin Sulfates / Dermatan Sulfate / Glycosaminoglycans Type of study: Screening_studies Limits: Animals / Child / Child, preschool / Humans / Infant / Newborn Language: En Year: 2011 Type: Article

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