Frequency of circulating Tregs with demethylated FOXP3 intron 1 in melanoma patients receiving tumor vaccines and potentially Treg-depleting agents.

de Vries, I Jolanda M; Castelli, Chiara; Huygens, Caroline; Jacobs, Joannes F M; Stockis, Julie; Schuler-Thurner, Beatrice; Adema, Gosse J; Punt, Cornelis J A; Rivoltini, Licia; Schuler, Gerold; Coulie, Pierre G; Lucas, Sophie

de Vries, I Jolanda M; Castelli, Chiara; Huygens, Caroline; Jacobs, Joannes F M; Stockis, Julie; Schuler-Thurner, Beatrice; Adema, Gosse J; Punt, Cornelis J A; Rivoltini, Licia; Schuler, Gerold; Coulie, Pierre G; Lucas, Sophie.

Affiliation

de Vries IJ; Department of Medical Oncology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, The Netherlands.

Clin Cancer Res ; 17(4): 841-8, 2011 Feb 15.

Article in En | MEDLINE | ID: mdl-21177412

Subject(s)

Cancer Vaccines/therapeutic use; DNA Methylation; Forkhead Transcription Factors/genetics; Melanoma/pathology; T-Lymphocytes, Regulatory/metabolism; Antibodies, Monoclonal/therapeutic use; Antibodies, Monoclonal, Humanized; Antineoplastic Agents/therapeutic use; Cell Count; Cyclophosphamide/therapeutic use; Daclizumab; Diphtheria Toxin/therapeutic use; Female; Genetic Markers/genetics; Humans; Immunoglobulin G/therapeutic use; Interleukin-2/therapeutic use; Introns; Lymphocyte Depletion; Male; Melanoma/immunology; Melanoma/therapy; Recombinant Fusion Proteins/therapeutic use; Retrospective Studies; T-Lymphocytes, Regulatory/pathology

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Full text: 1 Database: MEDLINE Main subject: T-Lymphocytes, Regulatory / Cancer Vaccines / DNA Methylation / Forkhead Transcription Factors / Melanoma Type of study: Observational_studies Limits: Female / Humans / Male Language: En Year: 2011 Type: Article

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