Effects of clarithromycin and dexamethasone on mucus production in isografted rat trachea.

Kitano, Masako; Ishinaga, Hajime; Shimizu, Takeshi; Takeuchi, Kazuhiko; Majima, Yuichi

Kitano, Masako; Ishinaga, Hajime; Shimizu, Takeshi; Takeuchi, Kazuhiko; Majima, Yuichi.

Affiliation

Kitano M; Department of Otorhinolaryngology - Head and Neck Surgery, Mie University Graduate School of Medicine, Tsu, Japan.

Pharmacology ; 87(1-2): 56-62, 2011.

Article in En | MEDLINE | ID: mdl-21228611

Subject(s)

Anti-Bacterial Agents/therapeutic use; Clarithromycin/therapeutic use; Dexamethasone/analogs & derivatives; Disease Models, Animal; Glucocorticoids/therapeutic use; Mucus/metabolism; Trachea/drug effects; Animals; Anti-Bacterial Agents/metabolism; Anti-Bacterial Agents/pharmacokinetics; Anti-Inflammatory Agents/metabolism; Anti-Inflammatory Agents/pharmacokinetics; Anti-Inflammatory Agents/therapeutic use; Clarithromycin/metabolism; Clarithromycin/pharmacokinetics; Dexamethasone/therapeutic use; Goblet Cells/drug effects; Goblet Cells/metabolism; Goblet Cells/pathology; Lipopolysaccharides/toxicity; Male; Metaplasia/chemically induced; Mucus/chemistry; Rats; Rats, Inbred F344; Secretory Pathway/drug effects; Severity of Illness Index; Trachea/metabolism; Trachea/pathology; Trachea/transplantation; Tracheitis/drug therapy; Tracheitis/metabolism; Tracheitis/pathology; Tracheitis/physiopathology; Transplantation, Isogeneic; Viscosity

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Full text: 1 Database: MEDLINE Main subject: Trachea / Dexamethasone / Clarithromycin / Disease Models, Animal / Glucocorticoids / Anti-Bacterial Agents / Mucus Limits: Animals Language: En Year: 2011 Type: Article

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