Activity profiles of 309 ToxCast&#8482; chemicals evaluated across 292 biochemical targets.

Knudsen, Thomas B; Houck, Keith A; Sipes, Nisha S; Singh, Amar V; Judson, Richard S; Martin, Matthew T; Weissman, Arthur; Kleinstreuer, Nicole C; Mortensen, Holly M; Reif, David M; Rabinowitz, James R; Setzer, R Woodrow; Richard, Ann M; Dix, David J; Kavlock, Robert J

Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.

Knudsen, Thomas B; Houck, Keith A; Sipes, Nisha S; Singh, Amar V; Judson, Richard S; Martin, Matthew T; Weissman, Arthur; Kleinstreuer, Nicole C; Mortensen, Holly M; Reif, David M; Rabinowitz, James R; Setzer, R Woodrow; Richard, Ann M; Dix, David J; Kavlock, Robert J.

Affiliation

Knudsen TB; National Center for Computational Toxicology (B205-01), Office of Research & Development, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. knudsen.thomas@epa.gov

Toxicology ; 282(1-2): 1-15, 2011 Mar 28.

Article in En | MEDLINE | ID: mdl-21251949

Subject(s)

Environmental Pollutants/toxicity; Toxicity Tests; Animal Use Alternatives; Animals; Automation, Laboratory; Cell-Free System; Data Interpretation, Statistical; Databases, Factual; Environmental Pollutants/classification; Enzyme Inhibitors/toxicity; High-Throughput Screening Assays; Humans; Ligands; Models, Biological; Osmolar Concentration; Pesticide Residues/toxicity; Rats; Reproducibility of Results; United States; United States Environmental Protection Agency

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Full text: 1 Database: MEDLINE Main subject: Toxicity Tests / Environmental Pollutants Type of study: Evaluation_studies / Prognostic_studies Limits: Animals / Humans Country/Region as subject: America do norte Language: En Year: 2011 Type: Article

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