Cell-to-cell variability in PI3K protein level regulates PI3K-AKT pathway activity in cell populations.

Yuan, Tina L; Wulf, Gerburg; Burga, Laura; Cantley, Lewis C

Yuan, Tina L; Wulf, Gerburg; Burga, Laura; Cantley, Lewis C.

Affiliation

Yuan TL; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.

Curr Biol ; 21(3): 173-83, 2011 Feb 08.

Article in En | MEDLINE | ID: mdl-21256021

Subject(s)

Class Ia Phosphatidylinositol 3-Kinase/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Cell Communication; Cell Line; Class Ia Phosphatidylinositol 3-Kinase/genetics; Class Ia Phosphatidylinositol 3-Kinase/physiology; Epidermal Growth Factor/pharmacology; Flow Cytometry; Humans; Phosphatidylinositol 3-Kinases/genetics; Phosphatidylinositol 3-Kinases/physiology; Phosphorylation; Signal Transduction

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Full text: 1 Database: MEDLINE Main subject: Phosphatidylinositol 3-Kinases / Proto-Oncogene Proteins c-akt / Class Ia Phosphatidylinositol 3-Kinase Limits: Humans Language: En Year: 2011 Type: Article

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