Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer.

Guo, Bao-Hong; Feng, Yan; Zhang, Rong; Xu, Li-Hua; Li, Man-Zhi; Kung, Hsiang-Fu; Song, Li-Bing; Zeng, Mu-Sheng

Guo, Bao-Hong; Feng, Yan; Zhang, Rong; Xu, Li-Hua; Li, Man-Zhi; Kung, Hsiang-Fu; Song, Li-Bing; Zeng, Mu-Sheng.

Affiliation

Guo BH; State Key Laboratory of Oncology in South China and Department of Experimental Research, Sun Yat-Sen University Cancer Center, Guangzhou, PR China.

Mol Cancer ; 10(1): 10, 2011 Jan 28.

Article in En | MEDLINE | ID: mdl-21276221

Subject(s)

Biomarkers, Tumor/metabolism; Breast Neoplasms/pathology; Neoplasm Invasiveness; Nuclear Proteins/metabolism; Proto-Oncogene Proteins/metabolism; Repressor Proteins/metabolism; Animals; Biomarkers, Tumor/genetics; Breast Neoplasms/metabolism; Breast Neoplasms/mortality; Cell Movement; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Female; Glycogen Synthase Kinase 3/physiology; Glycogen Synthase Kinase 3 beta; Humans; Kaplan-Meier Estimate; Lung Neoplasms/secondary; Mice; Mice, Nude; Middle Aged; Neoplasm Metastasis; Neoplasm Transplantation; Nuclear Proteins/genetics; Polycomb Repressive Complex 1; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins c-akt/physiology; Repressor Proteins/genetics; Signal Transduction; Snail Family Transcription Factors; Transcription Factors/physiology; Tumor Burden; Up-Regulation

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Full text: 1 Database: MEDLINE Main subject: Repressor Proteins / Breast Neoplasms / Nuclear Proteins / Biomarkers, Tumor / Proto-Oncogene Proteins / Neoplasm Invasiveness Type of study: Prognostic_studies Limits: Animals / Female / Humans / Middle aged Language: En Year: 2011 Type: Article

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