A common haplotype of the TNF receptor 2 gene modulates endotoxin tolerance.

Fairfax, Benjamin P; Davenport, Emma E; Makino, Seiko; Hill, Adrian V S; Vannberg, Fredrik O; Knight, Julian C

Fairfax, Benjamin P; Davenport, Emma E; Makino, Seiko; Hill, Adrian V S; Vannberg, Fredrik O; Knight, Julian C.

Affiliation

Fairfax BP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, United Kingdom.

J Immunol ; 186(5): 3058-65, 2011 Mar 01.

Article in En | MEDLINE | ID: mdl-21282507

Subject(s)

Endotoxins/pharmacology; Haplotypes; Immune Tolerance/genetics; Lipopolysaccharides/pharmacology; TNF Receptor-Associated Factor 2/genetics; Animals; Cells, Cultured; Cohort Studies; Endotoxins/immunology; Endotoxins/metabolism; Feedback, Physiological; Genetic Markers; Genotype; Humans; Leukocytes, Mononuclear/immunology; Leukocytes, Mononuclear/metabolism; Lipopolysaccharides/immunology; Lipopolysaccharides/metabolism; Macaca; Pan troglodytes; Polymorphism, Single Nucleotide; Pongo; Quantitative Trait Loci; TNF Receptor-Associated Factor 2/biosynthesis; TNF Receptor-Associated Factor 2/physiology; Tumor Necrosis Factor-alpha/antagonists & inhibitors; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/metabolism

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Full text: 1 Database: MEDLINE Main subject: Haplotypes / Lipopolysaccharides / TNF Receptor-Associated Factor 2 / Endotoxins / Immune Tolerance Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Year: 2011 Type: Article

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