Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma.

Deshpande, Vikram; Nduaguba, Afamefuna; Zimmerman, Stephanie M; Kehoe, Sarah M; Macconaill, Laura E; Lauwers, Gregory Y; Ferrone, Cristina; Bardeesy, Nabeel; Zhu, Andrew X; Hezel, Aram F

Deshpande, Vikram; Nduaguba, Afamefuna; Zimmerman, Stephanie M; Kehoe, Sarah M; Macconaill, Laura E; Lauwers, Gregory Y; Ferrone, Cristina; Bardeesy, Nabeel; Zhu, Andrew X; Hezel, Aram F.

Affiliation

Deshpande V; Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, USA.

BMC Cancer ; 11: 60, 2011 Feb 08.

Article in En | MEDLINE | ID: mdl-21303542

Subject(s)

Carcinoma/genetics; Gallbladder Neoplasms/genetics; Phosphatidylinositol 3-Kinases/genetics; Adult; Aged; Aged, 80 and over; Bile Duct Neoplasms/genetics; Bile Duct Neoplasms/metabolism; Bile Ducts, Intrahepatic/metabolism; Carcinoma/metabolism; Cholangiocarcinoma/genetics; Cholangiocarcinoma/metabolism; Class I Phosphatidylinositol 3-Kinases; Cohort Studies; DNA Mutational Analysis; Female; Gallbladder Neoplasms/metabolism; Genes, ras; Humans; Liver Neoplasms/genetics; Liver Neoplasms/metabolism; Male; Middle Aged; Phosphatidylinositol 3-Kinases/metabolism; Validation Studies as Topic

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Full text: 1 Database: MEDLINE Main subject: Carcinoma / Phosphatidylinositol 3-Kinases / Gallbladder Neoplasms Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Year: 2011 Type: Article

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