Triggered release from liposomes through magnetic actuation of iron oxide nanoparticle containing membranes.
Nano Lett
; 11(4): 1664-70, 2011 Apr 13.
Article
in En
| MEDLINE
| ID: mdl-21351741
ABSTRACT
The ideal nanoscale drug delivery vehicle allows control over the released dose in space and time. We demonstrate that this can be achieved by stealth liposomes comprising self-assembled superparamagnetic iron oxide nanoparticles (NPs) individually stabilized with palmityl-nitroDOPA incorporated in the lipid membrane. Alternating magnetic fields were used to control timing and dose of repeatedly released cargo from such vesicles by locally heating the membrane, which changed its permeability without major effects on the environment.
Full text:
1
Database:
MEDLINE
Main subject:
Pharmaceutical Preparations
/
Ferric Compounds
/
Nanocapsules
/
Liposomes
/
Membranes, Artificial
Language:
En
Year:
2011
Type:
Article