Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia.

Liebau, Max C; Höpker, Katja; Müller, Roman U; Schmedding, Ingolf; Zank, Sibylle; Schairer, Benjamin; Fabretti, Francesca; Höhne, Martin; Bartram, Malte P; Dafinger, Claudia; Hackl, Matthias; Burst, Volker; Habbig, Sandra; Zentgraf, Hanswalter; Blaukat, Andree; Walz, Gerd; Benzing, Thomas; Schermer, Bernhard

Liebau, Max C; Höpker, Katja; Müller, Roman U; Schmedding, Ingolf; Zank, Sibylle; Schairer, Benjamin; Fabretti, Francesca; Höhne, Martin; Bartram, Malte P; Dafinger, Claudia; Hackl, Matthias; Burst, Volker; Habbig, Sandra; Zentgraf, Hanswalter; Blaukat, Andree; Walz, Gerd; Benzing, Thomas; Schermer, Bernhard.

Affiliation

Liebau MC; Renal Division, Department of Medicine and Center for Molecular Medicine, University of Cologne, 50937 Cologne, Germany.

J Biol Chem ; 286(16): 14237-45, 2011 Apr 22.

Article in En | MEDLINE | ID: mdl-21357692

Subject(s)

Adaptor Proteins, Signal Transducing/metabolism; Cilia/metabolism; Focal Adhesion Kinase 2/metabolism; Gene Expression Regulation; Membrane Proteins/metabolism; Proteins/physiology; Tyrosine/chemistry; Cell Line; Cytoskeletal Proteins; Golgi Apparatus/metabolism; Humans; Kidney Diseases, Cystic/metabolism; Models, Biological; Mutation; Phosphorylation; Protein Binding; Tissue Distribution

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Full text: 1 Database: MEDLINE Main subject: Tyrosine / Proteins / Gene Expression Regulation / Cilia / Adaptor Proteins, Signal Transducing / Focal Adhesion Kinase 2 / Membrane Proteins Limits: Humans Language: En Year: 2011 Type: Article

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