Microbiological screening of Irish patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy reveals persistence of Candida albicans strains, gradual reduction in susceptibility to azoles, and incidences of clinical signs of oral candidiasis without culture evidence.

McManus, Brenda A; McGovern, Eleanor; Moran, Gary P; Healy, Claire M; Nunn, June; Fleming, Pádraig; Costigan, Colm; Sullivan, Derek J; Coleman, David C

McManus, Brenda A; McGovern, Eleanor; Moran, Gary P; Healy, Claire M; Nunn, June; Fleming, Pádraig; Costigan, Colm; Sullivan, Derek J; Coleman, David C.

Affiliation

McManus BA; Microbiology Research Unit, Division of Oral Biosciences, Dublin Dental University Hospital, University of Dublin, Trinity College Dublin, Dublin 2, Republic of Ireland.

J Clin Microbiol ; 49(5): 1879-89, 2011 May.

Article in En | MEDLINE | ID: mdl-21367996

Subject(s)

Azoles/pharmacology; Candida albicans/drug effects; Candida albicans/isolation & purification; Candidiasis, Oral/diagnosis; Drug Resistance, Fungal; Mass Screening/methods; Polyendocrinopathies, Autoimmune/diagnosis; Adolescent; Adult; Antifungal Agents/pharmacology; Candida albicans/classification; Candida albicans/genetics; Candidiasis, Oral/microbiology; Child; Child, Preschool; Female; Fluconazole/pharmacology; Humans; Incidence; Ireland; Itraconazole/pharmacology; Male; Mouth Mucosa/microbiology; Multilocus Sequence Typing; Mycological Typing Techniques; Polyendocrinopathies, Autoimmune/microbiology

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Full text: 1 Database: MEDLINE Main subject: Azoles / Candida albicans / Candidiasis, Oral / Mass Screening / Polyendocrinopathies, Autoimmune / Drug Resistance, Fungal Type of study: Diagnostic_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Country/Region as subject: Europa Language: En Year: 2011 Type: Article

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