Bradykinin receptor 1 activation exacerbates experimental focal and segmental glomerulosclerosis.

Pereira, Rafael L; Buscariollo, Bruna N; Corrêa-Costa, Matheus; Semedo, Patricia; Oliveira, Cassiano D; Reis, Vanessa O; Maquigussa, Edgar; Araújo, Ronaldo C; Braga, Tárcio T; Soares, Maria F; Moura, Ivan C; Malheiros, Denise M A C; Filho, Alvaro Pacheco-Silva; Keller, Alexandre C; Câmara, Niels O S

Pereira, Rafael L; Buscariollo, Bruna N; Corrêa-Costa, Matheus; Semedo, Patricia; Oliveira, Cassiano D; Reis, Vanessa O; Maquigussa, Edgar; Araújo, Ronaldo C; Braga, Tárcio T; Soares, Maria F; Moura, Ivan C; Malheiros, Denise M A C; Filho, Alvaro Pacheco-Silva; Keller, Alexandre C; Câmara, Niels O S.

Affiliation

Pereira RL; Departamento de Medicina, Laboratório de Imunologia Clínica e Experimental, Disciplina de Nefrologia, Universidade Federal de São Paulo, Brazil.

Kidney Int ; 79(11): 1217-27, 2011 Jun.

Article in En | MEDLINE | ID: mdl-21412216

Subject(s)

Bradykinin/analogs & derivatives; Glomerulosclerosis, Focal Segmental/chemically induced; Podocytes/drug effects; Receptor, Bradykinin B1/agonists; Signal Transduction/drug effects; Actinin/metabolism; Albuminuria/chemically induced; Albuminuria/metabolism; Albuminuria/prevention & control; Animals; Bradykinin/pharmacology; Bradykinin/toxicity; Bradykinin B1 Receptor Antagonists; Disease Models, Animal; Doxorubicin; Gene Expression Regulation/drug effects; Glomerulosclerosis, Focal Segmental/genetics; Glomerulosclerosis, Focal Segmental/metabolism; Glomerulosclerosis, Focal Segmental/pathology; Glomerulosclerosis, Focal Segmental/prevention & control; Heme Oxygenase-1/metabolism; Interleukin-1beta/metabolism; Intracellular Signaling Peptides and Proteins/metabolism; Macrophages/drug effects; Macrophages/metabolism; Male; Matrix Metalloproteinase 9/metabolism; Membrane Proteins/metabolism; Mice; Mice, Inbred BALB C; Podocytes/metabolism; Podocytes/pathology; RNA, Messenger/metabolism; Receptor, Bradykinin B1/genetics; Receptor, Bradykinin B1/metabolism; Time Factors; Tissue Inhibitor of Metalloproteinase-1/metabolism

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Full text: 1 Database: MEDLINE Main subject: Bradykinin / Glomerulosclerosis, Focal Segmental / Signal Transduction / Receptor, Bradykinin B1 / Podocytes Type of study: Prognostic_studies Language: En Year: 2011 Type: Article

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