Adenocarcinoma/drug therapy; Antihypertensive Agents/therapeutic use; Antineoplastic Agents/therapeutic use; Hypertension, Pulmonary/drug therapy; Iloprost/therapeutic use; Lung Neoplasms/drug therapy; Scleroderma, Systemic/complications; Vasodilator Agents/therapeutic use; Adenocarcinoma/secondary; Adenocarcinoma of Lung; Administration, Inhalation; Antihypertensive Agents/administration & dosage; Antineoplastic Agents/administration & dosage; Biopsy; Disease Progression; Familial Primary Pulmonary Hypertension; Fatal Outcome; Female; Gastrointestinal Diseases/etiology; Humans; Hypertension, Pulmonary/diagnosis; Hypertension, Pulmonary/etiology; Iloprost/administration & dosage; Immunohistochemistry; Lung Neoplasms/secondary; Middle Aged; Multimodal Imaging; Positron-Emission Tomography; Scleroderma, Systemic/diagnosis; Tomography, X-Ray Computed; Treatment Outcome; Vasodilator Agents/administration & dosage