Adenosine/metabolism; Gene Expression Regulation, Enzymologic/drug effects; Glycolysis/drug effects; Lipopolysaccharides/pharmacology; Macrophages, Peritoneal/enzymology; Phosphofructokinase-2/biosynthesis; Toll-Like Receptor 4/agonists; Adenosine/genetics; Adenosine Triphosphate/biosynthesis; Adenosine Triphosphate/genetics; Amino Acid Sequence; Animals; Cell Line; Fructosediphosphates/genetics; Fructosediphosphates/metabolism; Gene Expression Regulation, Enzymologic/physiology; Glycolysis/physiology; Hypoxia-Inducible Factor 1, alpha Subunit/genetics; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; Isoenzymes/biosynthesis; Isoenzymes/genetics; Macrophage Activation/drug effects; Macrophage Activation/physiology; Macrophages, Peritoneal/cytology; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Phosphofructokinase-2/genetics; Receptor, Adenosine A2A/genetics; Receptor, Adenosine A2A/metabolism; Receptor, Adenosine A2B; Sequence Deletion; Sp1 Transcription Factor/genetics; Sp1 Transcription Factor/metabolism; Toll-Like Receptor 4/genetics; Toll-Like Receptor 4/metabolism