Argatroban therapy in pediatric patients requiring nonheparin anticoagulation: an open-label, safety, efficacy, and pharmacokinetic study.

Young, G; Boshkov, L K; Sullivan, J E; Raffini, L J; Cox, D S; Boyle, D A; Kallender, H; Tarka, E A; Soffer, J; Hursting, M J

Young, G; Boshkov, L K; Sullivan, J E; Raffini, L J; Cox, D S; Boyle, D A; Kallender, H; Tarka, E A; Soffer, J; Hursting, M J.

Affiliation

Young G; Division of Hematology/Oncology, Children's Hospital Los Angeles, Los Angeles, California, USA. gyoung@chla.usc.edu

Pediatr Blood Cancer ; 56(7): 1103-9, 2011 Jul 01.

Article in En | MEDLINE | ID: mdl-21488155

Subject(s)

Hemorrhage/drug therapy; Pipecolic Acids/therapeutic use; Platelet Aggregation Inhibitors/therapeutic use; Thrombocytopenia/drug therapy; Thrombosis/drug therapy; Anticoagulants/adverse effects; Arginine/analogs & derivatives; Child; Child, Preschool; Female; Heparin/adverse effects; Humans; Infant; Liver Function Tests; Male; Pipecolic Acids/pharmacokinetics; Platelet Aggregation Inhibitors/pharmacokinetics; Prospective Studies; Sulfonamides; Survival Rate; Tissue Distribution; Treatment Outcome

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Full text: 1 Database: MEDLINE Main subject: Pipecolic Acids / Thrombocytopenia / Thrombosis / Platelet Aggregation Inhibitors / Hemorrhage Type of study: Clinical_trials / Observational_studies / Risk_factors_studies Limits: Child / Child, preschool / Female / Humans / Infant / Male Language: En Year: 2011 Type: Article

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