Perturbation of the Akt/Gsk3-ß signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs.

van Eyk, Clare L; O'Keefe, Louise V; Lawlor, Kynan T; Samaraweera, Saumya E; McLeod, Catherine J; Price, Gareth R; Venter, Deon J; Richards, Robert I

van Eyk, Clare L; O'Keefe, Louise V; Lawlor, Kynan T; Samaraweera, Saumya E; McLeod, Catherine J; Price, Gareth R; Venter, Deon J; Richards, Robert I.

Affiliation

van Eyk CL; Discipline of Genetics, School of Molecular and Biomedical Sciences and ARC Special Research Centre for the Molecular Genetics of Development, University of Adelaide, Adelaide SA 5005, Australia.

Hum Mol Genet ; 20(14): 2783-94, 2011 Jul 15.

Article in En | MEDLINE | ID: mdl-21518731

Subject(s)

Drosophila Proteins/metabolism; Gene Expression; Glycogen Synthase Kinase 3/metabolism; Neurodegenerative Diseases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; RNA/biosynthesis; Repetitive Sequences, Nucleic Acid; Signal Transduction; Animals; Drosophila Proteins/genetics; Drosophila melanogaster; Glycogen Synthase Kinase 3/genetics; Glycogen Synthase Kinase 3 beta; Neurodegenerative Diseases/genetics; Proto-Oncogene Proteins c-akt/genetics; RNA/genetics

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Full text: 1 Database: MEDLINE Main subject: RNA / Repetitive Sequences, Nucleic Acid / Signal Transduction / Gene Expression / Neurodegenerative Diseases / Drosophila Proteins / Glycogen Synthase Kinase 3 / Proto-Oncogene Proteins c-akt Limits: Animals Language: En Year: 2011 Type: Article

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