NADPH oxidase pathway is involved in aortic contraction induced by A3 adenosine receptor in mice.

El-Awady, Mohammed S; Ansari, Habib R; Fil, Daniel; Tilley, Stephen L; Mustafa, S Jamal

El-Awady, Mohammed S; Ansari, Habib R; Fil, Daniel; Tilley, Stephen L; Mustafa, S Jamal.

Affiliation

El-Awady MS; Department of Physiology and Pharmacology, West Virginia University, Morgantown, WV 26505, USA.

J Pharmacol Exp Ther ; 338(2): 711-7, 2011 Aug.

Article in En | MEDLINE | ID: mdl-21606175

Subject(s)

Aorta, Thoracic/metabolism; Muscle, Smooth, Vascular/enzymology; NADPH Oxidases/physiology; Receptor, Adenosine A3/physiology; Signal Transduction/physiology; Vasoconstriction/physiology; Animals; Aorta, Thoracic/enzymology; Enzyme Activation/drug effects; Enzyme Activation/genetics; Female; Fluoresceins/pharmacology; Male; Membrane Glycoproteins/metabolism; Membrane Glycoproteins/physiology; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular/drug effects; Muscle, Smooth, Vascular/physiology; NADPH Oxidase 2; NADPH Oxidases/metabolism; Reactive Oxygen Species/metabolism; Receptor, Adenosine A3/deficiency; Receptor, Adenosine A3/genetics; Signal Transduction/drug effects; Signal Transduction/genetics; Vasoconstriction/drug effects; Vasoconstriction/genetics

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Full text: 1 Database: MEDLINE Main subject: Aorta, Thoracic / Vasoconstriction / Signal Transduction / NADPH Oxidases / Receptor, Adenosine A3 / Muscle, Smooth, Vascular Limits: Animals Language: En Year: 2011 Type: Article

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