Airway Remodeling/physiology; Asthma/metabolism; Membrane Proteins/metabolism; Muscle, Smooth/metabolism; Respiratory System/metabolism; Airway Remodeling/drug effects; Airway Remodeling/genetics; Animals; Asthma/genetics; Asthma/pathology; Base Sequence; Case-Control Studies; Cell Line; Cell Proliferation; Chemokine CXCL10/metabolism; Chemokines/metabolism; Claudin-1; Cytokines/metabolism; DNA Primers/genetics; Dexamethasone/pharmacology; Disease Models, Animal; Female; Gene Expression/drug effects; Gene Knockdown Techniques; Humans; Inflammation/pathology; Interleukin-13/pharmacology; Interleukin-1beta/pharmacology; Interleukin-4/pharmacology; Male; Membrane Proteins/antagonists & inhibitors; Membrane Proteins/genetics; Mice; Mice, Inbred BALB C; Muscle, Smooth/pathology; Neovascularization, Pathologic; RNA, Small Interfering/genetics; Recombinant Proteins/pharmacology; Respiratory System/blood supply; Respiratory System/pathology; Tight Junctions/metabolism; Tumor Necrosis Factor-alpha/pharmacology