Phosphoinositide 3-kinase enhancer regulates neuronal dendritogenesis and survival in neocortex.

Chan, Chi Bun; Liu, Xia; Pradoldej, Sompol; Hao, Chunhai; An, Jie; Yepes, Manuel; Luo, Hongbo R; Ye, Keqiang

Chan, Chi Bun; Liu, Xia; Pradoldej, Sompol; Hao, Chunhai; An, Jie; Yepes, Manuel; Luo, Hongbo R; Ye, Keqiang.

Affiliation

Chan CB; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

J Neurosci ; 31(22): 8083-92, 2011 Jun 01.

Article in En | MEDLINE | ID: mdl-21632930

Subject(s)

Cell Survival/physiology; Dendrites/physiology; GTP Phosphohydrolases/physiology; Neocortex/growth & development; Neocortex/physiology; Nerve Tissue Proteins/physiology; Neurogenesis/physiology; Neurons/physiology; Animals; Apoptosis/genetics; Apoptosis/physiology; Brain-Derived Neurotrophic Factor/pharmacology; Brain-Derived Neurotrophic Factor/physiology; Cell Culture Techniques; Cell Survival/drug effects; Cell Survival/genetics; Dendrites/metabolism; Dendrites/ultrastructure; GTP Phosphohydrolases/genetics; Glutamic Acid/pharmacology; Infarction, Middle Cerebral Artery/metabolism; Infarction, Middle Cerebral Artery/physiopathology; Locomotion/genetics; Locomotion/physiology; Mice; Mice, Inbred C57BL; Mice, Knockout; Neocortex/cytology; Neocortex/metabolism; Nerve Tissue Proteins/genetics; Neurogenesis/genetics; Neurons/metabolism; Neurons/ultrastructure; Organ Size; PTEN Phosphohydrolase/genetics; PTEN Phosphohydrolase/physiology; Proto-Oncogene Proteins c-akt/physiology; Signal Transduction/genetics; Signal Transduction/physiology; Spatial Behavior/physiology

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Full text: 1 Database: MEDLINE Main subject: Cell Survival / Neocortex / Dendrites / Neurogenesis / GTP Phosphohydrolases / Nerve Tissue Proteins / Neurons Language: En Year: 2011 Type: Article

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