The sphingosine 1-phosphate receptor S1P2 maintains the homeostasis of germinal center B cells and promotes niche confinement.

Green, Jesse A; Suzuki, Kazuhiro; Cho, Bryan; Willison, L David; Palmer, Daniel; Allen, Christopher D C; Schmidt, Timothy H; Xu, Ying; Proia, Richard L; Coughlin, Shaun R; Cyster, Jason G

Green, Jesse A; Suzuki, Kazuhiro; Cho, Bryan; Willison, L David; Palmer, Daniel; Allen, Christopher D C; Schmidt, Timothy H; Xu, Ying; Proia, Richard L; Coughlin, Shaun R; Cyster, Jason G.

Affiliation

Green JA; Howard Hughes Medical Institute and Department of Microbiology and Immunology, San Francisco, California, USA.

Nat Immunol ; 12(7): 672-80, 2011 Jun 05.

Article in En | MEDLINE | ID: mdl-21642988

Subject(s)

B-Lymphocytes/immunology; Germinal Center/immunology; Homeostasis/immunology; Receptors, Lysosphingolipid/immunology; Animals; B-Lymphocytes/enzymology; Cell Survival/immunology; GTP-Binding Protein alpha Subunits, G12-G13/immunology; Germinal Center/cytology; Germinal Center/enzymology; Guanine Nucleotide Exchange Factors/immunology; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt/immunology; Rho Guanine Nucleotide Exchange Factors

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Full text: 1 Database: MEDLINE Main subject: B-Lymphocytes / Germinal Center / Receptors, Lysosphingolipid / Homeostasis Limits: Animals Language: En Year: 2011 Type: Article

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