Polo-like kinase 1 is a potential therapeutic target in human melanoma.

Jalili, Ahmad; Moser, Anna; Pashenkov, Mikhail; Wagner, Christine; Pathria, Gaurav; Borgdorff, Viola; Gschaider, Melanie; Stingl, Georg; Ramaswamy, Sridhar; Wagner, Stephan N

Jalili, Ahmad; Moser, Anna; Pashenkov, Mikhail; Wagner, Christine; Pathria, Gaurav; Borgdorff, Viola; Gschaider, Melanie; Stingl, Georg; Ramaswamy, Sridhar; Wagner, Stephan N.

Affiliation

Jalili A; Division of Immunology, Allergy and Infectious Diseases, Department of Dermatology, Medical University of Vienna, Vienna, Austria. ahmad.jalili@meduniwien.ac.at

J Invest Dermatol ; 131(9): 1886-95, 2011 Sep.

Article in En | MEDLINE | ID: mdl-21654832

Subject(s)

Cell Cycle Proteins/genetics; Melanoma/genetics; Melanoma/therapy; Protein Serine-Threonine Kinases/genetics; Proto-Oncogene Proteins/genetics; RNA, Small Interfering/pharmacology; Skin Neoplasms/genetics; Skin Neoplasms/therapy; Apoptosis/drug effects; Apoptosis/physiology; Cell Cycle Proteins/metabolism; Cell Line, Tumor; Cell Survival/drug effects; Cell Survival/physiology; Enzyme Inhibitors/pharmacology; Flavonoids/pharmacology; G1 Phase/physiology; Gene Expression Regulation, Enzymologic/physiology; Gene Expression Regulation, Neoplastic/physiology; Genomics; Humans; MAP Kinase Signaling System/drug effects; MAP Kinase Signaling System/physiology; Melanoma/secondary; Nevus, Pigmented/genetics; Nevus, Pigmented/pathology; Polymorphism, Single Nucleotide/genetics; Protein Serine-Threonine Kinases/metabolism; Proto-Oncogene Proteins/metabolism; Skin Neoplasms/pathology; Tumor Suppressor Protein p53/metabolism; Polo-Like Kinase 1

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Skin Neoplasms / Proto-Oncogene Proteins / Protein Serine-Threonine Kinases / Cell Cycle Proteins / RNA, Small Interfering / Melanoma Limits: Humans Language: En Year: 2011 Type: Article

Fulltext

XML

PubMed Links

Search on Google